Change the supplier and you change the price 3.9x.
Hold every spec identical. The same single-cell I2C chip costs $2.31 from Texas Instruments, $1.33 from Microchip and $5.23 from Analog Devices. No engineering explains that spread. Pin count and architecture need engineering in the room. Supplier choice does not, so procurement moves this one alone.
Rank suppliers on premium before you rank them on quote.